Poster Number ID# Titile First Author  May 22 Category: Molecular Biology P-A-1 20 Effects of Tax on PCNA Expression and Function Dustin C Edwards P-A-2 40 HTLV-1 Tax Induces a Novel Leukemogen Factor: the bHLH Transcription Factor TAL-1. Implication in LTR Regulation Jean-Michel Terme P-A-3 66 Characterization of the Promoter Region for HBZ Gene and Functional Analyses of Spliced and Unspliced HBZ Genes Mika Yoshida P-A-4 97 HTLV-1 Tax Activates CD69 Gene Expression Chie Ishikawa P-A-5 101 The HTLV-1 Tax Oncoprotein Interacts with the MCM2-7 Complex and Disregulates DNA Replication Mathieu Boxus P-A-6 127 Aberrant NF-kB Inducing Kinase Expression in Hematopoietic Cancer Cells and its Role in Cell Transformation. Yasunori Saitoh P-A-7 143 HTLV-1 Tax Oncoprotein Misappropriates huChk2 via Hyperactivation and Subcellular Redistribution Saurabh K Gupta P-A-8 153 HTLV1 Tax Induces IL-21 and IL-21R Gene Expression Mariko Mizuguchi P-A-9 166 Repression of the VEGF Promoter by HTLV-1 Tax Protein Karen Watters P-A-10 174 Evidence of Interaction Between HTLV-I and HTLV-II Tax Proteins with RelA/p65 Subunit of NF-kB Complex Maria Grazia Romanelli P-A-11 177 HTLV-1 Tax Expression Reduces the Histone:DNA Ratio in Human T-cell Lines James M Bogengerger P-A-12 180 HTLV-I Tax Protein is Phosphorylated in Vitro by Human Protein Kinase CK2 Carlo Bidoia P-A-13 186 Inhibition of VEGF-Mediated Signaling Blocks the Invasive Potential of Adult T-Cell Leukemia Cells through the Endothelium Marwan E El-Sabban P-A-14 188 HTLV-1 Infected Cell Lines are Susceptible to Cell Death Induced by Combination Treatment with AZT and Pharmacological Inhibitors of NF-kB. Claudia C Matteucci Virology P-A-15 33 Candidate Polyanionic Microbicides Inhibit HTLV-1 Infection Fusion and Receptor Interactions Daniela Römer P-A-16 60 Imbalance of Tumor Necrosis Factor Receptors during Progression in Bovine Leukemia Virus Infection   P-A-17 62 Tumor Necrosis Factor-alpha Genetic Polymorphism may Contribute to Progression of Bovine Leukemia Virus-Infection Satoru Konnai P-A-18 63 Interferon-gamma Expression Associated with Suppression of Bovine Leukemia Virus at the Early Phase of Infection in Sheep Tatsufumi Usui P-A-19 72 The Role of T-cell Co-stimulatory Molecule Expression in Human T-Lymphotropic Virus Type-1 Infection Tarek T Kattan P-A-20 74 RNA Helicase A Interacts with Divergent Lymphotropic Retroviruses and is Necessary for Human T-cell Leukemia Virus Type 1 Replication Cheryl Bolinger P-A-21 92 The Nuclear Import of the HTLV-I Tax Protein is Carrier and Energy Independent Takahiro Tsuji P-A-22 103 Human Brain Endothelial Cells Express High Levels of GLUT1 and Support Infection by HTLV Philippe Afonso P-A-23 110 In Vitro and In Vivo Effects of Recombinant Bovine Interferon-tau on Bovine Leukemia Virus Junko Kohara P-A-24 115 HTLV-1 can Infect Human Lung Epithelial Cells and Induce Gene Gxpression of Cytokines Chemokines and Cell Adhesion Molecules Hiromitsu Teruya P-A-25 125 Milk Whey or Milk-Derived Factors Facilitate HTLV-I Infection Masako Moriuchi P-A-26 140 STLV-1 Infection in Naturally Infected Mandrills an Attractive Model of HTLV-1 Infection for Studying the Pathogenesis of the Virus and for Testing a Therapeutic Vaccine Sandrine Souquière P-A-27 145 Relationship Between Polymorphism of BoLA Class IIa Region and Resistance for Development of Bovine Leukemia Virus (BLV)-induced Lymphoma Shin-nosuke Takeshima P-A-28 150 The Supersensitive Detection Method of HTLV-1 p40Tax Protein in the Peripheral Blood Tissue Specimen with Adult T-cell Leukemia Cells Kazuhisa Hasui P-A-29 185 HTLV-1 Subtype C Melanesian Genetic Variants of Vanuatu Archipelago and Solomon Islands Share a Common Ancestor Olivier Cassar P-A-30 196 A Novel High Throughput Quantum Dot-based Fluorescence Assay for the Quantitative Analyses of HTLV-1 Binding and Screening of Viral Binding Inhibitors Jaya Ahuja P-A-31 199 Phylogenetic Characterization of HTLV-1 from Different Populations in Argentina. Maria Emilia Eirin P-A-32 200 Expression of HTLV-1 oncoprotein Tax in adenovirus system in order to facilitate in vivo delivery of Tax into the central nervous system Zafar Khan P-A-33 201 Identification of a Novel Simian T-lymphotropic virus (STLV) Lineage in Two Monkey Species from Cameroon: High STLV Diversity at the Hunter-Primate Interface David M Sintasath P-A-34 205 Identification of HTLV-1 Tax amino acid signals and cellular factors involved in secretion of the viral oncoprotein Pooja Jain Hematology P-A-35 34 Factors Required for Long Survival in Adult T Cell Leukemia/Lymphoa Patients who Undergo Allogenic Hematopoetic STEM Cell Transplantation Shigeki Takemoto P-A-36 36 Deficiency of CTL Function in Adult T-cell leukemia Patients Mediated by Interaction of PD-1 and PD-L1 Tomohiro Kozako P-A-37 38 Human herpesvirus 6 Reactivation in Patients with Adult T Cell Leukemia Masao Ogata P-A-38 61 Soluble IL-2 Receptor and CD30 as Predictive Tumor Markers for Complete Remission or Poor Prognosis of Adult T Cell Leukemia/Lymphoma Shigeki Takemoto P-A-39 82 Bone Marrow Transplantation from Unrelated Donors for Patients with Adult T-cell Leukemia/Lymphoma - Single Center Experience - Masamichi Hara P-A-40 83 Unique Relapse Pattern and Outcome of Treatment after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Adult T-Cell Leukemia/Lymphoma (ATLL) Ryuji Tanosaki P-A-41 86 Strategy for Maintenance of Complete Remission without ALllogeneic Hematopoetic Stem Cell Transplantation in Adult T Cell Leukemia/Lymphoma Shigeki Takemoto P-A-42 88 Pilot Study of Reduced-intensity Cord Blood Transplantation (RICBT) for Advanced Adult T-cell Leukemia/Lymphoma (ATLL). Atsushi Wake P-A-43 109 Graft-versus-adult T-cell Leukemia/Lymphoma (Gv-ATL) Effect in ATL Patients after Allogeneic Stem Cell Transplantation Kentaro Yonekura P-A-44 147 Expression of the Toll-like Receptor System in Adult T-cell Leukemia/Lymphoma. Kazushi Tanimoto P-A-45 152 Smouldering Adult T-cell Leukemia (ATL). Is it a Leukemia? Kazuo Tamura P-A-46 158 Augmented Expression of Programmed Death-1 in CD4+ T Cells in Patients with Adult T Cell Leukemia/Lymphoma Takatoshi Shimauchi P-A-47 163 Retrospective Analysis of Allogeneic Hematopoietic Stem Cell Transplantation for ATLL of Kyushu Area in Japan: Comparison Between CST and RIST Takuya Fukushima P-A-48 169 A Pilot Study of Irinotecan Hydrochloride (CPT-11) plus Cisplatin (CDDP) as Salvage Therapy for Relapseed and Refractory ATLL Takuya Fukushima P-A-49 183 A Phase II Study of the Efficacy and Toxicity of Alemtuzumab (Campath®) for Treatment of Human T Cell Lymphotrophic Virus-1 (HTLV-1)-associated Adult T Cell Leukemia/Lymphoma (ATL) John Morris P-A-50 222 Clinical experience on ATLL in the Sanin Area Yoshiaki Iwashita P-A-51 251 Preemptive therapy of cytomegalovirus infection in an adult T-cell leukemia patient. Masaki Toshima P-A-52 271 Association between HTLV-I provirus and clinical course in adult T-cell leukemia Kisato Nosaka P-A-53 285 Relapsed adult T-cell leukemia/lymphoma limited in the skin after allogeneic stem cell transplantation Shigeru Kusumoto P-A-54 316 IN VIVO EXPRESSION OF GENES OF THE pX REGION IN HAM/TSP AND ATL PATIENTS AND ASYMPTOMATIC HTLV-1 CARRIERS. Olivier Verlaeten P-A-55 321 An exceptional pediatric case of ATL with a monoclonal CD4+CD8+ phenotype and an indolent course Lourdes Farre P-A-56 328 Therapeutic Potential of Arsenic Trioxide with or without Interferon-± for Relapsed/Refractory Adult T-Cell Leukemia/Lymphoma Kazuo Tamura P-A-97 359 Primary cutaneous type adult T-cell leukemia/ lymphoma(ATLL): A study on HTLV-1 proviral DNA load in peripheral blood mononuclear cells Masahiro Amano P-A-98 236 Search for ATL Markers by Serum Proteomic Analysis; Association of ATL with Complement System Yo-ichi Ishida Animal Models P-A-57 78 HBZ Transgenic Mice Mimic Skin and Lung Diseases Associated with HTLV-I Yorifumi Satou P-A-58 121 Anti-ATL Effects of a Novel Synthetic Retinoid Am80 (Tamibarotene) through Inhibition of NF-κB Tetsuro Nakazato P-A-59 138 A Novel Bioluminescent Mouse Model and Effective Therapy for Adult T-cell Leukemia/Lymphoma Sherry Shu P-A-60 284 HTLV-1 Infection Greatly Modified The Characteristics of Radiation Induced Lymphoma in Mice Masanao Miwa Epidemiology P-A-61 32 Awareness of Mother-to-Child Transmission of Human T-cell lymphotropic virus (HTLV) type 1 through Breastfeeding in a Small Group of HTLV-Positive Women in Maripasoula and Papaichton French Guiana. Tolullah Oni P-A-62 35 Evaluation of HTLV1 as a Risk Factor in Cervical Carcinoma-Khorasan Fatemeh H Shandiz P-A-63 46 DC-SIGN (CD209) Promoter Region Polymorphisms: Populational Distribution in Brazilian Ethnic Groups and Association with HTLV-1 Infection Simone Kashima P-A-64 47 Comparison of HTLV-1/2 Screening Assays: an Optimal Efficiency of the Current HTLV-1/2 Diagnosis Carolina C Berini P-A-65 57 Serological Epidemiological and Molecular Characteristics of HTLV-1/2 Infection in Pregnant Women in Gabon Central Africa Sonia Lekana-Douki P-A-66 65 Detection Quantification and Correlation of Extrachromosomal HTLV-I DNA with HTLV-I Viral Load and Disease Status. Fabiola Martin P-A-67 71 Epidemiology of Hepatitis B (HBV) and C (HCV) Infections in Patients Infected by HIV and/or HTLV in Bahia Brazil   P-A-68 75 HTLV- I Infection is not Associated with a Higher Risk of Death in Peruvian HIV-infected Patients Jaime A Collins P-A-69 107 Effect of Influenza Vaccination on Proviral Load in Human T-Lymphotropic Virus Type 1 (HTLV-1)-Infected Individuals Mayumi Kurimura P-A-70 128 Transient Increase in HTLV-I Proviral Load upon Hepatitis-B e-Antigen/Antibody Seroconversion in a Co-Infected Individual Hiroyuki Moriuchi P-A-71 132 Postgenomic Up-regulation of CCL3L1 Expression in HTLV-2-infected Persons Curtails HIV-1 Replication Elisabetta Pilotti P-A-72 137 Clinical and Epidemiological Aspects of HTLV-1/2 Infections in a Highly Endemic Isolated Population of Remote Village in Gabon Central Africa Gerald Ngema Ondo P-A-73 141 Serological Patterns of HTLV-I/II Among High-risk Populations Attended at Public Health Units of São Paulo Brazil Fabricio Jacob P-A-74 146 Human T-lymphotropic Virus Type 1 as a Risk Factor for Atherosclesosis Hiroaki Takeoka P-A-75 155 Serum Anti-Tax Antibody Correlates to Lower Neutrophil Counts in Patients with HTLV-I Infection Heiichiro Hamada P-A-76 159 Occupational Therapeutical Program with Carrying Patients of Virus HTLV I: the Challenges of a New Approach. Isa J Coutinho P-A-77 172 T-regulatory Cell Population Expansion in HTLV-1 Patients with Strongyloides stercoralis co-infection Martin Montes P-A-78 178 Seroprevalence and Molecular Epidemiology Study of HTLV-1 Isolates from three Villages of the São Francisco Valley Bahia Brazil. Filipe Rego P-A-79 193 HTLV-2 a and b Subtypes among Injecting Drug Users (IDUs) in Argentina. Mirna Marcela Biglione P-A-80 203 DIAGNOSIS AND PHYLOGENETIC CHARACTERIZATION OF HTLV-1/2 INFECTION IN PREGNANT WOMEN FROM ARGENTINA. Maria Emilia Eirin P-A-81 308 HTLV-1 AND TUBERCULOSIS Edgar Carvalho Late Submission P-A-82 326 HTLV-1 uveitis and viral load in PBMC (JSPFAD study) Yoichi Iwanaga P-A-83 327 The Tax Oncoprotein of HTLV-I is Acetylated by p300 in a Phosphorylation-dependent manner Julie Lodewick P-A-84 328 Inhibition of p53 function by the Tax oncoprotein of HTLV-1 requires Tax ubiquitination but not NF-kappaB activity Isabelle Lamsoul P-A-85 329 HTLV-1/2 in a Public Transfusion Center in Belo Horizonte – Aspects of Hemovigilance Maria Sueli N Lopes P-A-86 330 IL-10 produced by CD4+ and CD8+ T-cells as a putative immunoregulatory mechanism to counterbalance the monocyte-derived TNF-a and guarantee the asymptomatic chronic HTLV-I infection Olindo A. Martins-Filho P-A-87 331 The GIPH experience: a cohort study of individuals with HTLV-1/2 Anna Bárbara F Carneiro-Proietti P-A-88 332 VESTIBULAR EVOKED MYOGENIC POTENTIAL FOR EVALUATING MEDULAR INJURY RELATED TO HTLV-1 Lilian Felipe P-A-89 333 ATLL IN NEW YORK CITY: A REVIEW FROM COLUMBIA UNIVERSITY MEDICAL CENTER Adrienne A Phillips P-A-90 334 Inhibition of Human T-lymphotropic Virus type I Integrase by Dicaffeoylquinic Acids extracted from Coffee seeds (Coffea arabica) Paula Ordonez P-A-91 335 Ex vivo lymphocyte Fas expression increases early upon HTLV-1 infection but does not reflect clinical status in ID, HAM/TSP and ATL patients Johan Van Weyenbergh P-A-92 336 Applicability of Immunoglobulin G, detected by flow cytometry, as a diagnostic tool in HTLV-1 infection Jordana G. Alves Coelho dos Reis P-A-93 337 In vitro response to IFN correlates with survival in ATL patients Ricardo Khouri P-A-94 338 Follow-up of immunological and viral parameters of asymptomatic HTLV-1 infected individuals in two different periods: applicability for prognosis and intervention in therapeutics Jaqueline G Souza P-A-95 339 HTLV-1 MYELOPATHY SOON AFTER HIGH DOSE CORTICOSTEROID THERAPY FOR TREATING ADULT T-CELL LEUKAEMIA Denise U Gonçalves P-A-96 340 HOW DIZZINESS MAY BE RELATED TO INITIAL HAM/TSP Lilian Felipe Workshop Basic P-A-98 53 Early Spatial and Temporal Virus Spread in Rabbits Infected Intravenously with HTLV-1 Rashade A H Haynes P-A-99 299 Temporal Regulation of HTLV-1 gene expression Ilaria Cavallari P-A-100 133 HTLV-3Pyl43: Complete Nucleotide Sequence and Characterization of the Human Tax3 Protein Sara Calattini P-A-101 54 Human T-lymphotropic Virus Type 1 p30(II) Activates DNA Damage Signaling Pathway with Enhanced ³H2AX Foci Formation and Phosphorylation of ATM at S-1981 Antara Datta P-A-102 301 Importance of signal peptide removal palmitoylation and dimerization of the HTLV-1 p12 protein complex Risaku Fukumoto P-A-103 98 Proteasome-dependent Ubiquitin-independent Degradation of c-Jun Mediated by HTLV-1 HBZ Osamu Isono P-A-104 212 Inhibition of double-strand DNA break repair by hnRNP B1 mediated through interaction with DNA-dependent protein kinase complex in adult T-cell leukemia Eisaburo Sueoka P-A-105 257 TSLC1 induces formation of lamellipodia through activation of Rac in the HTLV-1 infected T cells and the ATL cells. Mari Masuda P-A-106 325 Transcriptional Regulation of Telomerase through IL-2 Signaling Pathways Marcia Bellon P-A-107 69 Ubiquitylated Tax Activates IKK on a Centrosome-associated IKK Signalosome Youmna Kfoury P-A-108 295 Heptad Repeats Regulate Protein Phosphatase 2A Recruitement to IKKgamma/NEMO and are Tageted by HTLV-1 Tax Sohee Hong P-A-109 111 A Role of HTLV-I Tax in Expression of the Human Telomerase Reverse Transcriptase (hTERT) Gene in Human T Cells. Toshifumi Hara P-A-110 304 Tax-dependent hTERT transcriptional repression depends on a specific hTERT promoter occupancy that only involves a restricted fraction of the hTERT promoter peptidome. Franck Mortreux P-A-111 136 Comparative Analysis of Sub-cellular Distribution of HTLV-I and HTLV-II Tax Proteins Marco Turci P-A-112 162 HTLV-1 Tax Protein and ICAM-1 act Synergistically on the T-Cell Signalling Pathways to Trigger the MTOC Polarization Mohamed Nejmeddine P-A-113 179 Interaction of HTLV I Tax with the Human Oncoprotein BCL-6 Jonathan Dean P-A-114 181 Tax Abolishes Histone H1 Repression of p300 Acetyltransferase Activity at the HTLV-1 Promoter Kasey L Konesky P-A-115 252 Tax-induced recruitment of TORC family coactivators is required for transcriptional activation of HTLV-I LTR Yeung-Tung Siu P-A-116 85 Repression of HTLV-LTR Promoter Activity by SUV39H1 - Tax Interaction Aya Misawa P-A-117 318 Interaction of HTLV-1 Tax with a histone H3K4 methyltransferase SMYD3 induces cell cycle dependent subcellular di Keiyu Yamamoto       Poster Number ID# Titile First Author  May 24 Molecular Biology P-B-1 202 Generation of T cell monocyte B cell and progenitor cell lines carrying integrated HTLV-1 LTRs and microRNA profiling of the effects of Tax in the context of a stably integrated LTR Saifur Rahman P-B-2 209 CPG ISLAND METHYLATOR PHENOTYPE (CIMP) PROMOTES THE PROGRESSION OF ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL). Takashi Oka P-B-3 211 ABERRANT DNA METHYLATION IS ASSOCIATED WITH THE CLINICOPATHOLOGIC CHARACTERISTICS IN PATIENTS WITH ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL). Takashi Oka P-B-4 227 Involvement of Fra-2 and JunD in CCR4 expression and cell proliferation in adult T-cell leukemia Takashi Nakayama P-B-5 230 CARM1 enhances transcription of the HTLV-1 LTR through a direct interaction with Tax protein Soo-Jin Jeong P-B-6 246 HTLV-1 Tax-induced CCL22 promotes cell-cell interactions between HTLV-1-infected cells and peripheral blood CCR4+CD4+ T cells Kunio Hieshima P-B-7 275 Down-regulation of PIP3 inositol phosphatase expression by HTLV-I Tax via NF-kB pathway Kiyohito Tsuchiya P-B-8 286 The MHC class II transactivator CIITA blocks the transcriptional activity of both HTLV-2 Tax-2 and HTLV-1 Tax-1 Giovanna Tosi P-B-9 296 Synergistic apoptotic effect of NF-ºB and CDK inhibitors in HTLV-1 infected cells. Wen-I Yeh P-B-10 297 Actin enhances Tax-dependent transcription from the HTLV-1 LTR. Utibe Akpan P-B-11 315 Human T cell leukemia virus type 1 (HTLV-1) Tax-mediated NF-kB activation is independent of Lys-63-linked type polyubiquitination Jin Gohda P-B-12 323 A cooperation of Tax-1 with CRMP-2 to modulate T lymphocyte migration in HTLV-1-infected patients Michel Varrin-Doyer P-B-13 326 Regulation of Telomerase Activity and Telomere Length in HTLV-I-mediated T-cell Transformation Christophe Nicot Virology P-B-14 206 Interplay of dendritic cell surface receptors and adhesion molecules with respect to HTLV-1 binding entry and transmission Sharron Manuel P-B-15 210 Phylogenetic analysis of known exogenous and endogenous retroviral sequences gag pol and env: comparison with taxonomic structure and function of retroviruses. Bernd Kitze P-B-16 214 Mapping the molecular characteristics of Brazilian HTLV-1 Env (gp46) and Pol amino acid sequences for vaccine design. Aline Cristina Mota-Miranda P-B-17 249 Infection of CD34+ cells with HTLV-1 and HTLV-2 Tax chimeras   P-B18 254 Expression of apoptosis-associated genes and NK receptor gene in peripheral blood mononuclear cells of sheep infected with bovine leukemia virus Michihiro Takagi P-B-19 255 Syncytium-forming Ability and Expression on the Cell Surface of Bovine Leukemia Virus Envelope Glycoprotein Are Regulated by YXXL Motif of Transmembrane Subunit Yoko Aida P-B-20 261 Role of glial cells in central nervous system injury of human retroviral infection. HuiQin Xing P-B-21 274 Roles of HSPG and NRP1 in HTLV-1 entry Sophie Lambert P-B-22 277 The LASP HTLV-1 automated subtyping tool (http://lasp.cpqgm.fiocruz.br/virus-genotype/html/subtypinghtlv.html) Luiz Alcantara P-B-23 283 Detection of BLV in frozen semen samples by PCR assay Maria Jose Dus Santos P-B-24 289 Effect of Lactoferrin on HTLV-1 Infection Masakazu Tanaka P-B-25 290 Suppression of Viral Gene Expression in Bovine Leukemia Virus-Associated B-cell Malignancy: Interplay of Epigenetic Modifications Leading to Chromatin with a Repressive Histone Code Makram Merimi P-B-26 292 Functional Characterization of p13 a mitochondrial protein coded by HTLV-1 Enrica Cannizzaro P-B-27 310 Virulence genetic markers in the LTR of naturally occurring variants of Bovine Leukemia Virus from Argentina. Sabrina M Rodríguez P-B-28 312 Naturally occurring BLV-LTR variants show differential binding with transcriptional regulator E2F-4. Sabrina M Rodríguez P-B-29 313 GLUT1 is not the primary receptor but is associated with cell-cell transmission of HTLV-1. Karen Yao P-B-30 327 HTLV-I Rex and p30 Interactions Govern the Switch Between Virus Latency and Replication Christophe Nicot P-B-115 243 Sensitive Detection of Proviral Bovine Leukemia Virus by PCR after in vitro Cultivation of Peripheral Blood Leukocytes Seiko Shuto P-B-116 244 A Rapid and Sensitive Diagnosis of Bovine Leukemia Virus Infection Using the Loop-Mediated Isothermal Amplification Assay Chiho Komiyama Immunology P-B-31 21 Pro-inflammatory Actions of β-adrenoceptor Antagonism in vivo: Enhancement of Innate IFN-γ Production and MHC Class II and Co-stimulatory Molecule Expression Noreen T Boyle P-B-32 84 Genetic Stability of HTLV-I Despite Antiviral Pressures by Cytotoxic T Lymphocytes Ryuji Kubota P-B-33 89 Impairment of Treg-specific Foxp3 Expression by HTLV-I-induced Dysregulation of TGF-beta Signaling Christian W Grant P-B-34 119 Regulation of the pre-TCRalpha Gene Transcription by Tax in Human Immature Thymocytes Mélanie Wencker P-B-35 130 Conformation-specific Antibodies Targeting the Trimer-of-hairpins Motif of the HTLV-1 Trans-membrane Glycoprotein David W Brighty P-B-36 139 Effect of Tax on Gene Expression During Human T-cell Differentiation Mélanie Wencker P-B-37 148 Presence of Tax-specific Cytotoxic T Lymphocytes in Adult T-cell Leukemia Patients and their Functional Failure. Ayako Takamori P-B-38 149 Diversity in Tax Specific T-cell Responses among Asymptomatic HTLV-I Carriers Yukiko Shimizu P-B-39 151 Analysis of Immunosuppressive Function of Foxp3 Expressing HTLV-I-infected Cells in a Rat Model Ryo Takayanagi P-B-40 164 Polymorphisms in Cytokine Genes could be Involved with Disease in HTLV-1 Infected Individuals from Salvador Bahia Brazil. Sandra Rocha Gadelha P-B-41 168 Neutralising Monoclonal Antibodies Targeting the Human T-cell Leukaemia Virus type 1 Surface Glycoprotein Subunits Chien-wen S Kuo P-B-42 191 In Vivo Selection of Human T Cell Lymphotropic Virus Type-1 Specific CD4+ Cells by Disease Susceptive Class II Allele and Immunodominant Peptide Complex in HTLV-1 Associated Neurological Disease Hirohisa Nose P-B-43 192 Modulation of Dendritic Cell Maturation Functions and Antigen-specific Immune Response by HTLV-1 Tax Protein Pooja Jain P-B-44 204 Immune Stimulation of LTR-Tax Transgenic CD4+T-cells Induces Hyper-proliferation Hyper-responsiveness and Prolonged Cell Survival Alison Y Swaims P-B-45 259 Highly Specific Inhibition of Tax-activated Transcription by Anti-Tax Intrabodies. David Brighty P-B-97 60 Imbalance of tumor necrosis factor receptors during progression in bovine leukemia virus infection Satoru Konnai Pthophysiology P-B-46 31 Transcriptional Regulation of Parathyroid Hormone-Related Protein Promoter P2 by NF-ºB in Adult T-cell Leukemia/Lymphoma Murali Nadella P-B-47 241 Rosemary Extract and Its Biological Active Substances Carnosic Acid and Carnosol Inhibit Growth of ATL Cells.; Proteomic Analysis of ATL Cells. Yo-ichi Ishida P-B-48 266 Phospholipid scramblase-1 involved in ATLL cell proliferation Yves Lepelletier P-B-49 267 Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL) Ryu-ich Fukuda P-B-50 317 Overexpressed Ezrin as a basis for enhanced migration of ATL cells Wakako Tsuchida Epidemiology P-B-51 216 Molecular epidemiology of HTLV-1 in the North of Brazil Aline Cristina Mota-Miranda P-B-52 218 ATLL & HTLV1 infection in Ishikawa Japan. Yasufumi Masaki P-B-53 220 Long-term abnormalities of complete blood counts in human T-lymphotropic virus type I and II (HTLV-I and -II) infection. Anthony Yeo P-B-54 223 Determinants of Follow-Up Rates in a Prospective Cohort Study of HTLV Infection Deborah A DeVita P-B-55 238 Epitopes of anti-197 antibody may correlate to the onset of HTLV-1-associated diseases. Eijiro Kojima P-B-56 240 Analysis of clonal expansion of HTLV-1 infected cells in the children in Jamaica Akihiko Okayama P-B-57 258 HTLV-2/HIV-1 dually infected individuals: analysis of the expression of surface markers related to impairment of cytolytic functions Paola Costa P-B-58 272 WHAT HAVE BEEN HAPPENING WITH THOSE HTLV-2-ASSOCIATED MYELONEUROPATHY PATIENTS FROM PORTO ALEGRE SINCE 1994 ? Marcio Menna-Barreto P-B-59 282 Quinoline compounds decrease in vitro spontaneous proliferation and proviral load of peripheral blood mononuclear cells (PBMC) from HTLV-1 -infected individuals. Ana Beatriz Guimaraes-Correa P-B-60 291 High prevalence of HTLV-1 infection among relatives of patients with HTLV-1-associated adult T-cell malignancies (HAATM) in Peru Miguel Cabada P-B-61 302 HAART stimulates HTLV-1 replication in HTLV-1/HIV coinfected patients. Carole Pomier P-B-63 309 HIV and HTLV-1 infection are frequent among patients with herpes zoster in Peru Elsa González Lagos Neurology P-B-64 45 Neuromyelitis Optica Secondary to HTLV-1 Infection (a propos of one case) Stéphane Olindo P-B-65 79 High Expression of CD28 Co-stimulatory Molecule and Low Expresion of CTLA4 Inhibitory Molecule on CD4+CD25+ T cells in HTLV-I Associated Myelopathy (HAM/TSP) Yoshihisa Yamano P-B-66 99 Increased CMV-specific CTL Associated with Decreased Expression of Foxp3 in HAM/TSP Daisuke Hayashi P-B-67 105 Spontaneous CD8 T Cell Degranulation in Patients with Human T Lymphocyte Virus Type I-associated Neurological Disease. Yoshimi Enose-Akahata P-B-68 114 The Involvement of Integrins/Ligands Signaling in HTLV-I Production from HTLV-I-infected T Cell Lines Derived from Patients with HTLV-I Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Naomi Fukushima P-B-69 118 Valproate does not Impair CTL Lysis Efficiency in HAM/TSP Patients Nicolas Gillet P-B-70 122 The Prevalence of Bladder Symptoms in Patients with HTLV-I Associated Myelopathy. Alexandra Fedina P-B-71 154 Which Outcome Measures to use for HTLV-1-Associated Myelopathy? Adine Adonis P-B-72 171 HTLV-1 Proviral Load in Peripheral Mononuclear Cells Quantified in TSP/HAM Oligosymptomatic Patients and Asymptomatic HTLV-1 Carriers Viviana Nilla Gallazzi Olavarria P-B-73 175 Mutations in U3-LTR Region of HTLV-1 could be Associated with HAM/TSP in Infected Individuals From Salvador Bahia Brazil. Sergio A Pereira P-B-74 182 MiR-17-5p and miR-374 are Differentially Expressed in CD8+ T Cells from Asymptomatic and HAM/TSP Patients Simone Kashima P-B-75 194 Development of a Multi-dimensional Scale for Evaluation of HTLV-1-associated Myelopathy Patients Andre L A Oliveira P-B-76 213 Isolated bladder dysfunction in HTLV-1 infection Marcus Tulius Silva P-B-77 215 HTLV-1-associated myelopathy and multisystem atrophy Marcus Tulius Silva P-B-78 217 A new schedule to intravenous methylprednisolone in HAM/TSP: an open label trial Marcus Tulius Silva P-B-79 219 Subacute HAM/TSP in a Brazilian cohort of HTLV-1-infected individuals Marco Lima P-B-80 256 Evaluation of dysfunction with HAM and the usefulness of the physiotherapy Yuriko Nakata-Kudo P-B-81 260 Gait analysis of HAM patient Motoki Okuda P-B-82 270 T-Cell Activation of Lymphocytes from HTLV-1 Infected Individuals is Independent of Spontaneous PBMC Proliferation. Rita Elizabeth Mascarenhas P-B-83 320 Phase I/II study of HTLV-I-associated myelopathy/tropical spastic paraparesis using a humanized monoclonal antibody that blocks IL-15 (Part I: study design). Unsong Oh Late Submission P-B-84 342 HAM/TSP AND ATL IN A YOUNG PATIENT WITH CRANIAL NERVE INVOLVIMENT AS INITIAL MANIFESTATION Lilian Felipe P-B-85 343 17²-Estradiol Hormone Levels are Decreased in HTLV-1 Infected Female Patients Luciana D Carvalho P-B-86 344 T Lymphocyte Proliferation and Disease Induced by HTLV-1 Infection of Humanized NOD/SCID Mice Prabal Banerjee P-B-87 345 HTLV-1 infection of CD34+ human hematopoietic progenitor cells suppress multilineage hematopoiesis and retards cell cycle progression by modulation of Survivin and p21cip/waf1 expression Prabal Banerjee P-B-88 346 HTLV-1 infection of primary CD4+T cells down-modulates ICAM-1 and -2 expressions and protects the infected cells from autologous NK cell mediated cytotoxicity Prabal Banerjee P-B-89 351 Deguelin Inhibits STAT5 Phosphorylation and Induces Apoptosis in Human T-cell Leukemia Virus Type I-infected Cell Line KUT1 Shigeki Ito P-B-90 352 The HTLV-1-Encoded Tax Protein Induces CREB Phosphorylation Young-Mi Kim P-B-91 353 Trend in Prevalence of Human T-lymphotropic Virus Type-1 (HTLV-1) Infection in Japanese Blood Donors, Nagasaki, 1999 to 2006 Masako Iwanaga P-B-92 355 Allogeneic Bone Marrow Transplantation for Adult T-cell Leukemia/Lymphoma (ATL) from Unrelated Donors. Feasibility and Utility of Reduced Intensity Conditioning for Bone Marrow Transplantation Tetsuya Eto P-B-93 356 Higher Tax Expression and HTLV-1 Replication In Vitro by Selective Ablation of the Initiation Codon of the Orf II p30II and p13II Proteins Valerio W Valeri P-B-94 357 Protein Isoforms Encoded by the HTLV-1 p30II Minimal cDNA Negatively Regulate Viral Expression Vibeke Andresen P-B-95 358 Open Longitudinal Study to Assess the Use of Corticosteroid Therapy in TSP/HAM Patients Mariana TRCG Crota Workshop Clinical P-B-96 96 Identification of Integration Site of HTLV-Ⅰ Takashi Moritoyo P-B-98 165 Osteoporosis in Young HTLV-1 Carriers: a New Incapacity Disease for a Neglected Population. Antonio Carlos Silva-Santos P-B-99 189 Detection of HTLV-2 Infection in Peruvian Female Sex Workers Pablo E Campos P-B-100 68 Prevalence of Hepatitis B (HBV) and C (HCV) Infections is Higher and Routes of Infection Differ for Patients Co-infected by HIV and HTLV Compared to Individuals Infected by a Single Retrovirus Marcia C. S. Moreira P-B-101 80 The Proteasome Inhibitor Bortezomib Induces Apoptosis and Enhances Suberoylanilide Hydroxamic Acid (SAHA) Induced Cell Death in HTLV-1 Infected Cell Lines and ATLL Cells. Masaki Ri P-B-102 120 A Novel IKK Inhibitor IMD-0354 Inhibits the Growth and Survival of ATL Cells both in vitro and in vivo Shin Uota P-B-103 294 HTLV-1 Tax transgenic ARF-null mice: A new model of high penetrance spontaneous osteosarcoma Daniel Rauch P-B-104 44 Allogeneic Hematopoietic Stem Cell Transplantation for Adult T-Cell Leukemia: Result of a Single Cente Hideo H Koh P-B-105 50 A Pilot Trial of Alemtuzumab (Campath-1H) and Dose-Adjusted EPOCH (DA-EPOCH) in CD52-Expressing Aggressive T-Cell Malignancies John Janik P-B-106 43 Open Label Study of the Effect of Valproic Acid in HAM/TSP (Preliminary Rresults of Clinical Data) Stéphane Olindo P-B-107 232 ACTIVATION OF LATENT PROVIRUS : NEW THERAPY FOR HTLV-1-ASSOCIATED MYELOPATHY/TROPICAL SPASTIC PARAPARESIS ? (a proof-of-concept study) Agnès Lezin P-B-108 229 In vivo selection of HTLV-1 specific CD4+ cells by disease susceptive class II allele and immunodominant peptide complex in HTLV-1–associated neurological disease. Hirohisa Nose P-B-109 233 HLA-A*2402 determines a risk of HAM/TSP independently from the HTLV-I proviral load. Norihiro Takenouchi P-B-110 131 HAM/TSP is a Central Axonopathie Originated by an Axonoplasmic Transport Disturbance Luis Cartier P-B-111 116 Kinetics of HTLV-1 Proviral Loads after allogeneic Hematopoietic Stem Cell Transplantation using Reduced Intensity Conditioning for Adult T-cell Leukemia/Lymphoma Atae Utsunomiya P-B-112 156 Epigenetically Dintinct Malignant Cell Population forms Lymphoma-involving Lesions in Acute Type Adult T–Cell Leukemia/Lymphoma (ATLL) Takashi Oka P-B-113 161 Clinical Significance of Serum TARC/CCL17 in ATLL Patients: High TARC/CCL17 Level is a Significant Unfavorable Prognostic Factor. Atsushi Inagaki P-B-114 237 Establishment of "PCR Array System" for specific detection of ATL cells in vivo. Aiko Matsubara